Trypanosoma cruzi calreticulin (TcCRT) is a virulence factor that binds complement C1. thus inhibiting the activation of the classical complement pathway and generating pro-phagocytic signals that increase parasite infectivity. In a previous work. we characterized a clonal cell line lacking one TcCRT allele (TcCRT+/-) and another overexpressing it (TcCRT+). https://bellfordtoysandhobbiers.shop/product-category/dice-sets/
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